INT178633

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.21
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.26
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pgr) nucleolus (Pgr) nucleus (Pgr)
enzyme binding (Pgr) cytoplasm (Pgr)
Anatomy Link Frequency
brain 4
Pgr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 23 99.78 Very High Very High Very High
Dopamine 92 99.22 Very High Very High Very High
addiction 2 89.20 High High
agonist 30 83.72 Quite High
amygdala 68 81.84 Quite High
anesthesia 5 52.96 Quite High
Neurotransmitter 4 48.80 Quite Low
imagery 4 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 9 79.08 Quite High
Decapitation 4 54.64 Quite High
Cancer 57 50.00 Quite Low
Targeted Disruption 3 47.72 Quite Low
Aids-related Complex 14 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 2 5.00 Very Low Very Low Very Low
Spontaneous Abortion 1 5.00 Very Low Very Low Very Low
Adenocarcinoma 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the effects of the PI3-K/Act pathway on PR expression is complex, because Cue and coworkers [57] found an indication of an IGF-I-induced inhibition of PR expression mediated through the PI3-K/Act cascade – an activity completely independent of ER-?.
Negative_regulation (inhibition) of Gene_expression (expression) of PR
1) Confidence 0.21 Published 2004 Journal Breast Cancer Res Section Body Doc Link PMC468665 Disease Relevance 0.21 Pain Relevance 0
PSK 3668 administered systemically blocks ER binding [33] and ER-induced PR expression [34] in the adult rat brain, as well as female sexual behavior [32].
Negative_regulation (blocks) of Gene_expression (expression) of PR in brain
2) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2359852 Disease Relevance 0.05 Pain Relevance 0.33
That is, DA D1-like receptor antagonist treatment reduces PR expression within restricted brain regions in neonatal male and female rats [17].
Negative_regulation (reduces) of Gene_expression (expression) of PR in brain associated with dopamine and antagonist
3) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2359852 Disease Relevance 0 Pain Relevance 0.53

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox