INT178773

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Context Info
Confidence 0.49
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.01
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (App) Golgi apparatus (App) plasma membrane (App)
extracellular matrix organization (App) DNA binding (App) cytoplasm (App)
App (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 22 99.68 Very High Very High Very High
Inflammation 76 99.42 Very High Very High Very High
Inflammatory mediators 7 78.04 Quite High
Inflammatory response 11 71.92 Quite High
cINOD 13 45.16 Quite Low
fibrosis 5 33.64 Quite Low
Hippocampus 10 7.00 Low Low
Inflammatory marker 10 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 115 99.42 Very High Very High Very High
Drug Induced Neurotoxicity 1 97.16 Very High Very High Very High
Disease 114 92.92 High High
Targeted Disruption 6 77.00 Quite High
Neurodegenerative Disease 1 69.72 Quite High
Aging 2 63.16 Quite High
Infection 49 62.76 Quite High
Periodontal Disease 52 50.00 Quite Low
Disease Progression 1 43.72 Quite Low
Pathologic Processes 1 41.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This finding reproduces in part a study reporting up-regulation of APP mRNA and protein, and increased production of A?
Positive_regulation (reproduces) of Regulation (regulation) of APP mRNA
1) Confidence 0.49 Published 2004 Journal J Neuroinflammation Section Body Doc Link PMC500868 Disease Relevance 0.08 Pain Relevance 0
Systemic inflammation and cytokine production can augment the regulation of APP and A?
Positive_regulation (augment) of Regulation (regulation) of APP associated with inflammation and cytokine
2) Confidence 0.36 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2626915 Disease Relevance 0.93 Pain Relevance 0.32

General Comments

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