INT178774

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Context Info
Confidence 0.49
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.17
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (App) Golgi apparatus (App) plasma membrane (App)
extracellular matrix organization (App) DNA binding (App) cytoplasm (App)
App (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 14 99.60 Very High Very High Very High
Inflammation 51 87.64 High High
Hippocampus 11 59.88 Quite High
cINOD 19 36.44 Quite Low
fibrosis 5 24.92 Low Low
agonist 12 5.00 Very Low Very Low Very Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 24 100.00 Very High Very High Very High
Targeted Disruption 8 100.00 Very High Very High Very High
Disease 46 99.72 Very High Very High Very High
INFLAMMATION 62 87.64 High High
Aging 3 60.60 Quite High
Urological Neuroanatomy 3 59.24 Quite High
Fibrosis 5 24.92 Low Low
Hydrocephalus 19 23.28 Low Low
Aggression 1 12.84 Low Low
Cerebral Amyloid Angiopathy 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
1 induces the transcription of the APP gene, and the production of APP and A?
Positive_regulation (induces) of Transcription (transcription) of APP
1) Confidence 0.49 Published 2004 Journal J Neuroinflammation Section Body Doc Link PMC500868 Disease Relevance 0.07 Pain Relevance 0
Indeed transgenic mice overexpressing human amyloid precursor protein (APP) develop early AD-like changes, including diffuse, extracellular A?
Positive_regulation (Indeed) of Transcription (develop) of amyloid precursor protein associated with targeted disruption, alzheimer's dementia and disease
2) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2366070 Disease Relevance 1.10 Pain Relevance 0.31

General Comments

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