INT17883

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Context Info
Confidence 0.44
First Reported 1980
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 8
Total Number 9
Disease Relevance 3.59
Pain Relevance 3.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (MRAP) plasma membrane (MRAP) cytoplasm (MRAP)
Anatomy Link Frequency
lymphocytes 2
MRAP (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 46 99.72 Very High Very High Very High
rheumatoid arthritis 6 97.52 Very High Very High Very High
Arthritis 2 54.72 Quite High
backache 1 41.44 Quite Low
Disease Link Frequency Relevance Heat
Low Back Pain 47 99.72 Very High Very High Very High
Recurrence 3 98.24 Very High Very High Very High
Rheumatoid Arthritis 6 97.52 Very High Very High Very High
Disease 3 71.12 Quite High
Arthritis 2 54.72 Quite High
Sacroiliitis 3 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The influence of HLA-B27 antigen on clinical, radiological and laboratory features of rheumatoid arthritis (RA) was studied.
Regulation (influence) of B27 associated with rheumatoid arthritis
1) Confidence 0.44 Published 1991 Journal Acta Med Iugosl Section Abstract Doc Link 1950638 Disease Relevance 0.59 Pain Relevance 0.23
Previously the highest probability of recurrence was 0.0785 in the case of an affected mother's son and it increased to 0.1416 when the B-27 antigen positive affected mother had a B-27 positive son.
Regulation (affected) of B-27 associated with recurrence
2) Confidence 0.44 Published 1984 Journal Ann. Hum. Genet. Section Abstract Doc Link 6608913 Disease Relevance 0.42 Pain Relevance 0.16
Aim of this study was to investigate of frequency of B27 subtypes in Croatian AS patients and B27 positive healthy controls.
Regulation (controls) of B27 associated with spinal inflammation
3) Confidence 0.14 Published 2001 Journal Reumatizam Section Abstract Doc Link 12476735 Disease Relevance 0.56 Pain Relevance 0.62
Group of 50 AS patients and 38 B27 positive controls were typed for B27 subtypes by PCR-SSP method.
Regulation (controls) of B27 associated with spinal inflammation
4) Confidence 0.14 Published 2001 Journal Reumatizam Section Abstract Doc Link 12476735 Disease Relevance 0.55 Pain Relevance 0.62
An antiserum to one isolate (427) of Klebsiella lysed the lymphocytes of B27 positive AS patients but not of B27 positive or B27 negative controls.
Regulation (controls) of B27 in lymphocytes associated with spinal inflammation
5) Confidence 0.07 Published 1980 Journal J Clin Lab Immunol Section Abstract Doc Link 7381924 Disease Relevance 0.65 Pain Relevance 0.74
An antiserum to one isolate (427) of Klebsiella lysed the lymphocytes of B27 positive AS patients but not of B27 positive or B27 negative controls.
Regulation (controls) of B27 in lymphocytes associated with spinal inflammation
6) Confidence 0.07 Published 1980 Journal J Clin Lab Immunol Section Abstract Doc Link 7381924 Disease Relevance 0.66 Pain Relevance 0.74
The TNF-alpha genotypes were equally prevalent in B27 positive AS and healthy matched B27 positive controls.
Regulation (controls) of B27
7) Confidence 0.03 Published 2001 Journal J. Rheumatol. Section Body Doc Link 11409121 Disease Relevance 0.05 Pain Relevance 0
The TNF-alpha genotypes were equally prevalent in B27 positive AS and healthy matched B27 positive controls.
Regulation (controls) of B27
8) Confidence 0.03 Published 2001 Journal J. Rheumatol. Section Body Doc Link 11409121 Disease Relevance 0.05 Pain Relevance 0
HLA-B27 and B60 were associated with the disease in probands, and the rate of disease concordance was significantly increased among DZ twin pairs in which the co-twin was positive for both B27 and DR1.
Regulation (positive) of B27
9) Confidence 0.02 Published 1997 Journal Arthritis Rheum. Section Body Doc Link 9336417 Disease Relevance 0.05 Pain Relevance 0

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