INT178840

Context Info Confidence 0.25 First Reported 2004 Last Reported 2010 Negated 2 Speculated 1 Reported most in Body Documents 5 Total Number 5 Disease Relevance 0.78 Pain Relevance 0.14

Golgi apparatus (GOPC) plasma membrane (GOPC) cytoplasm (GOPC)

Anatomy Link Frequency neurite 2 GOPC (Homo sapiens)

Pain Link Frequency Relevance Heat agonist 84 100.00 Somatostatin 5 20.96 Nerve growth factor 7 5.00 induced neuropathy 3 5.00 peripheral neuropathy 2 5.00 Neurotransmitter 2 5.00 Spinal cord 1 5.00 b2 receptor 1 5.00 Chemotherapy induced neuropathy 1 5.00 alcohol 1 5.00

Disease Link Frequency Relevance Heat Death 1 100.00 Acromegaly 7 99.20 Congenital Anomalies 4 95.84 Toxicity 32 89.28 Cancer 18 67.16 Adenoma 14 61.92 Thyroid Disease 13 38.36 Nodular Goiter 2 30.24 Stress 2 9.48 Pituitary Cancer 11 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

One and four years after treatment, the fecal microbial communities had partially recovered to their pre-treatment compositions, however these were still separated along CA axis 2 (Fig. 6B).

Spec (partially) Regulation (recovered) of Localization (separated) of Fig

1) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844414 Disease Relevance 0 Pain Relevance 0

328 in response to primary agonist stimulation (Fig. 3B and D, respectively), it partially and significantly impaired desensitization of TP?

Regulation (response) of Localization (stimulation) of Fig associated with agonist

2) Confidence 0.11 Published 2007 Journal Biochim Biophys Acta Section Body Doc Link PMC2680961 Disease Relevance 0 Pain Relevance 0.14

By comparison, in control experiments, the L-NAME analogue D-NAME (1 mmol/L) had no effect at all on histamine-stimulated acid secretion (Fig. 2b).

Neg (no) Regulation (effect) of Localization (secretion) of Fig

3) Confidence 0.10 Published 2004 Journal BMC Gastroenterol Section Body Doc Link PMC514546 Disease Relevance 0 Pain Relevance 0

One patient had overt acromegaly, and two others exhibited a definitely abnormal GH secretion pattern (Fig. 5), which resembled the TSH pattern.

Regulation (abnormal) of Localization (secretion) of Fig associated with acromegaly

4) Confidence 0.09 Published 2008 Journal Pituitary Section Body Doc Link PMC2712623 Disease Relevance 0.32 Pain Relevance 0

M had no effect on cell death or neurite outgrowth (Fig. 1b), although a 10 ?

Neg (no) Regulation (effect) of Localization (outgrowth) of Fig in neurite associated with death

5) Confidence 0.06 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1950519 Disease Relevance 0.46 Pain Relevance 0

General Comments

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