INT178868

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Context Info
Confidence 0.42
First Reported 2004
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.52
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ESR1) enzyme binding (ESR1) DNA binding (ESR1)
protein complex (ESR1) cytoplasm (ESR1) signal transduction (ESR1)
Anatomy Link Frequency
nucleus 2
ESR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 12 92.80 High High
antagonist 7 53.64 Quite High
metalloproteinase 1 18.08 Low Low
cINOD 3 13.96 Low Low
depression 8 8.76 Low Low
Neurotransmitter 11 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 48 97.80 Very High Very High Very High
Cancer 22 92.32 High High
Colon Cancer 8 57.92 Quite High
Cognitive Disorder 5 52.64 Quite High
Disease 16 50.00 Quite Low
Mental Disorders 3 50.00 Quite Low
Prolactinoma 1 29.24 Quite Low
Apoptosis 37 9.12 Low Low
Depression 6 8.76 Low Low
INFLAMMATION 1 5.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
mRNA transcript abundance and to examine their impact on transactivation of ER?
Spec (examine) Regulation (impact) of Spec (examine) Positive_regulation (transactivation) of ER
1) Confidence 0.42 Published 2007 Journal Breast Cancer Res Section Body Doc Link PMC2246173 Disease Relevance 0 Pain Relevance 0
induction of progesterone receptors in the ventromedial nucleus.98 ER?
Regulation (ventromedial) of Positive_regulation (nucleus.98) of ER in nucleus
2) Confidence 0.15 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971739 Disease Relevance 0.05 Pain Relevance 0.05
In addition to occupancy of the ER, I am postulating that these drugs, at ?
Spec (postulating) Regulation (postulating) of Positive_regulation (occupancy) of ER
3) Confidence 0.03 Published 2004 Journal BMC Cancer Section Body Doc Link PMC514706 Disease Relevance 0.46 Pain Relevance 0.03

General Comments

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