INT179170

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Context Info
Confidence 0.43
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.88
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAPK14) nucleoplasm (MAPK14) signal transduction (MAPK14)
nucleus (MAPK14) response to stress (MAPK14) cytoplasm (MAPK14)
MAPK14 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 103 99.48 Very High Very High Very High
Inflammation 53 88.32 High High
antagonist 10 73.16 Quite High
Catecholamine 16 54.24 Quite High
Inflammatory stimuli 5 5.00 Very Low Very Low Very Low
dexamethasone 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Kinase C inhibitor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 174 99.88 Very High Very High Very High
INFLAMMATION 60 88.32 High High
Stress 14 88.24 High High
Atherosclerosis 18 76.88 Quite High
Disease 4 76.16 Quite High
Diabetes Mellitus 10 50.56 Quite High
Cancer 7 50.00 Quite Low
Necrosis 5 50.00 Quite Low
Insulin Resistance 11 5.00 Very Low Very Low Very Low
Acute-phase Reaction 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
p42/44 MAP Kinase and JNK pathways do not influence LPS induced TNFalpha synthesis
Protein_catabolism (pathways) of p42/44 MAP Kinase
1) Confidence 0.43 Published 2010 Journal J Inflamm (Lond) Section Body Doc Link PMC2819999 Disease Relevance 0.16 Pain Relevance 0
B degradation (Fig. 4B) or JNK1/2 or p38 phosphorylation (supplementary Fig.
Protein_catabolism (degradation) of p38
2) Confidence 0.12 Published 2010 Journal Diabetes Section Body Doc Link PMC2797946 Disease Relevance 0.26 Pain Relevance 0.26
B nor p38 MAPK was activated further by IL-1?
Neg (nor) Protein_catabolism (nor) of p38
3) Confidence 0.07 Published 2004 Journal BMC Immunol Section Body Doc Link PMC521685 Disease Relevance 0.46 Pain Relevance 0.17

General Comments

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