INT17919

Context Info Confidence 0.40 First Reported 1991 Last Reported 1991 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.14 Pain Relevance 0.06

nucleus (Trh, Fos) aging (Fos) DNA binding (Fos) response to stress (Fos) cytoplasm (Trh) extracellular region (Trh)

Anatomy Link Frequency neurons 1 Trh (Rattus norvegicus) Fos (Rattus norvegicus)

Pain Link Frequency Relevance Heat Enkephalin 1 57.92 Intracerebroventricular 1 49.64

Disease Link Frequency Relevance Heat Stress 2 73.96

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Double staining for Fos and TRH, CRF, or met-Enk revealed that thyroidectomy induced Fos-like IR specifically within TRH-, but not within CRF-, or met-Enk, expressing neurons in the pPVN.

TRH Positive_regulation (induced) of Fos in neurons

1) Confidence 0.40 Published 1991 Journal Endocrinology Section Abstract Doc Link 1954900 Disease Relevance 0.14 Pain Relevance 0.06

General Comments

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