INT179217

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Context Info
Confidence 0.11
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.91
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ATP1A4) transmembrane transport (ATP1A4)
Anatomy Link Frequency
alveolar cells 1
ATP1A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
unmyelinated 38 98.48 Very High Very High Very High
sodium channel 13 97.68 Very High Very High Very High
agonist 62 95.20 Very High Very High Very High
gABA 69 93.24 High High
c fibre 42 92.52 High High
dorsal root ganglion 13 76.72 Quite High
Sciatic nerve 2 51.76 Quite High
GABA receptor 1 24.76 Low Low
nociceptor 2 14.88 Low Low
Inflammation 22 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adult Respiratory Distress Syndrome 92 95.72 Very High Very High Very High
Pressure And Volume Under Development 39 86.80 High High
Cv General 4 Under Development 14 82.00 Quite High
Ganglion Cysts 13 76.72 Quite High
Nociception 8 7.84 Low Low
INFLAMMATION 32 5.00 Very Low Very Low Very Low
Injury 11 5.00 Very Low Very Low Very Low
Lung Injury 9 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low
Sepsis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Peripheral [34] as well as central [35] unmyelinated axons hyperpolarize upon repetitive activation, an effect attributed to an increase in Na-K-ATPase activity [36].
Positive_regulation (increase) of Na-K-ATPase associated with unmyelinated
1) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2808338 Disease Relevance 0.14 Pain Relevance 0.99
To summarize, beta-2 adrenergic receptor stimulation increases sodium, chloride, and fluid absorption by increasing the activity of the Na,K-ATPase pump and by increasing the activity of epithelial apical sodium channels in type I and type II alveolar cells.
Positive_regulation (increasing) of Na,K-ATPase in alveolar cells associated with sodium channel
2) Confidence 0.06 Published 2004 Journal Crit Care Section Body Doc Link PMC522843 Disease Relevance 0.77 Pain Relevance 0.36

General Comments

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