INT179233

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6, GSR) cytoplasm (IRF6, GSR) mitochondrion (GSR)
small molecule metabolic process (GSR) oxidoreductase activity (GSR) nucleus (IRF6)
IRF6 (Homo sapiens)
GSR (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 11 98.72 Very High Very High Very High
Inflammation 17 70.80 Quite High
rheumatoid arthritis 1 65.68 Quite High
cva 5 5.00 Very Low Very Low Very Low
opiate 3 5.00 Very Low Very Low Very Low
medulla 3 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Catecholamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 2 95.92 Very High Very High Very High
Sepsis 33 95.20 Very High Very High Very High
INFLAMMATION 19 70.80 Quite High
Asthma 1 68.40 Quite High
Inflammatory Bowel Disease 1 67.76 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 66.16 Quite High
Rheumatoid Arthritis 1 65.68 Quite High
Adult Respiratory Distress Syndrome 1 63.92 Quite High
Necrosis 5 5.00 Very Low Very Low Very Low
Adrenal Insufficiency 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both endotoxin and lipopolysaccaride (LPS) have been shown to decrease GR affinity for ligand, mainly by inducing cytokine expression [53].
LPS Negative_regulation (decrease) of GR Binding (affinity) of associated with cytokine
1) Confidence 0.03 Published 2004 Journal Crit Care Section Body Doc Link PMC522845 Disease Relevance 0.83 Pain Relevance 0.25

General Comments

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