INT179248

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Context Info
Confidence 0.40
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 4.65
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GSR) mitochondrion (GSR) small molecule metabolic process (GSR)
oxidoreductase activity (GSR) cytoplasm (GSR)
GSR (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 2 100.00 Very High Very High Very High
cytokine 15 96.32 Very High Very High Very High
imagery 17 94.72 High High
Inflammatory response 5 85.20 High High
Inflammation 33 81.24 Quite High
corticosteroid 9 71.12 Quite High
rheumatoid arthritis 1 59.60 Quite High
Pain 9 51.68 Quite High
Somatosensory cortex 4 25.72 Quite Low
isoflurane 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stroke 108 99.92 Very High Very High Very High
Stress 207 99.70 Very High Very High Very High
Sepsis 33 87.60 High High
Shock 4 85.76 High High
INFLAMMATION 39 85.20 High High
Pressure And Volume Under Development 8 65.92 Quite High
Death 8 61.96 Quite High
Injury 5 61.20 Quite High
Adult Respiratory Distress Syndrome 1 61.08 Quite High
Rheumatoid Arthritis 1 59.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since the reported enjoyment was not dependent on the baseline period, the dependence of GSR on enjoyment in our experiment must have been due entirely to the differentiated response to the aversive stimulus caused by the two different tasks.
Positive_regulation (due) of Positive_regulation (dependence) of GSR associated with addiction
1) Confidence 0.40 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2517650 Disease Relevance 0.05 Pain Relevance 0.15
induced GR upregulation without increasing GR mRNA [69].
Positive_regulation (induced) of Positive_regulation (upregulation) of GR
2) Confidence 0.26 Published 2004 Journal Crit Care Section Body Doc Link PMC522845 Disease Relevance 0.72 Pain Relevance 0.19
The main finding of the present study revealed an additive effect of stress and stroke to enhance GR activation in the lesion hemisphere.
Positive_regulation (enhance) of Positive_regulation (activation) of GR associated with stress and stroke
3) Confidence 0.12 Published 2010 Journal Exp Transl Stroke Med Section Body Doc Link PMC2954925 Disease Relevance 1.07 Pain Relevance 0.07
While enhanced GR activation occurred without concomitant changes in infarct size, diminished recovery in these animals suggests that elevated GC levels are detrimental to functional outcome.
Positive_regulation (enhanced) of Positive_regulation (activation) of GR
4) Confidence 0.12 Published 2010 Journal Exp Transl Stroke Med Section Body Doc Link PMC2954925 Disease Relevance 1.07 Pain Relevance 0.08
Exaggerated functional loss in stressed rats was related to increased GR activation in the lesion hemisphere as indicated by nuclear GR location.


Positive_regulation (increased) of Positive_regulation (activation) of GR
5) Confidence 0.12 Published 2010 Journal Exp Transl Stroke Med Section Abstract Doc Link PMC2954925 Disease Relevance 0.94 Pain Relevance 0
Enhanced GR activation in the lesion hemisphere suggests altered sensitivity of the HPA axis induced by stress.
Positive_regulation (Enhanced) of Positive_regulation (activation) of GR associated with stress
6) Confidence 0.12 Published 2010 Journal Exp Transl Stroke Med Section Body Doc Link PMC2954925 Disease Relevance 0.79 Pain Relevance 0.07

General Comments

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