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Context Info
Confidence 0.27
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.80
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (AKT2) transport (AKT2) mitochondrion (AKT2)
carbohydrate metabolic process (AKT2) cytoplasm (AKT2) cytosol (AKT2)
AKT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 27 94.24 High High
Kinase C 1 69.20 Quite High
cytokine 14 54.00 Quite High
chemokine 100 50.00 Quite Low
Inflammatory response 2 49.48 Quite Low
Catecholamine 2 32.40 Quite Low
alcohol 1 32.00 Quite Low
antagonist 10 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
cva 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ovarian Cancer 85 99.76 Very High Very High Very High
Brain Hemorrhage 1 99.24 Very High Very High Very High
Vasculitis 1 94.60 High High
Myocardial Infarction 1 93.24 High High
Cv Unclassified Under Development 1 91.88 High High
Reperfusion Injury 1 91.48 High High
Cancer 158 90.96 High High
Apoptosis 4 89.68 High High
INFLAMMATION 32 78.84 Quite High
Carcinoma 2 76.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, FGF1, MYC, EGFR, KRAS, HER2, and AKT2, have been also associated with ovarian cancer [56].
AKT2 Binding (associated) of associated with ovarian cancer
1) Confidence 0.27 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2798669 Disease Relevance 1.10 Pain Relevance 0
Similarly, binding of glucocorticoids to the GR-stimulated phosphatidylinositol 3-kinase and protein kinase Akt, leading to endothelial NOS activation and nitric oxide dependent vasorelaxation, is the mechanism by which glucocorticoids decreased vascular inflammation and reduced myocardial infarct size following ischaemia/reperfusion injury in mice [103].

protein kinase Akt Binding (binding) of associated with reperfusion injury, inflammation, cv unclassified under development, vasculitis and myocardial infarction
2) Confidence 0.03 Published 2004 Journal Crit Care Section Body Doc Link PMC522845 Disease Relevance 0.70 Pain Relevance 0.15

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