INT17937

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Context Info
Confidence 0.27
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.48
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Isl1) intracellular (Isl1) DNA binding (Isl1)
Anatomy Link Frequency
motoneurons 1
Isl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 2 98.12 Very High Very High Very High
Spinal cord 33 80.52 Quite High
anesthesia 2 69.16 Quite High
Catecholamine 16 15.60 Low Low
monoamine 3 5.00 Very Low Very Low Very Low
Action potential 2 5.00 Very Low Very Low Very Low
Sciatic nerve 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
lumbar region 1 5.00 Very Low Very Low Very Low
Peripheral nerve stimulation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 8 79.84 Quite High
Spinal Cord Injury 25 67.72 Quite High
Injury 13 59.72 Quite High
Contusions 2 9.60 Low Low
Cicatrix 5 5.00 Very Low Very Low Very Low
Familial Adenomatous Polyposis 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Weight Loss 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Paralysis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We determined that MP are able to mature and develop fundamental functions of normal motoneurons in vitro (expressing OLIG2, ISL1, and HOXC5), including directional growth of long axons, confirming the results from the previous study [11].
Gene_expression (expressing) of ISL1 in motoneurons
1) Confidence 0.27 Published 2010 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2996083 Disease Relevance 0.19 Pain Relevance 0.11
Carboxypeptidase-H is a molecule expressed within islet secretory granules and neurendocrine cells.
Gene_expression (expressed) of islet
2) Confidence 0.09 Published 1991 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 1955501 Disease Relevance 0.15 Pain Relevance 0.10
Using serum from a prediabetic patient as a probe, we screened 0.5 x 10(6) recombinants from a rat islet lambda gt11 expression library.
Gene_expression (expression) of islet
3) Confidence 0.09 Published 1991 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 1955501 Disease Relevance 0.13 Pain Relevance 0.08
Islet insulin content
Gene_expression (content) of Islet
4) Confidence 0.03 Published 2003 Journal BMC Endocr Disord Section Body Doc Link PMC153518 Disease Relevance 0 Pain Relevance 0.07

General Comments

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