INT179406

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Context Info
Confidence 0.12
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.07
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Elk1)
Elk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Visceral pain 2 82.84 Quite High
Inflammation 1 78.04 Quite High
Central nervous system 1 61.04 Quite High
Hippocampus 22 52.08 Quite High
long-term potentiation 1 47.36 Quite Low
amygdala 12 45.52 Quite Low
depression 3 25.60 Quite Low
nMDA receptor 5 5.00 Very Low Very Low Very Low
Glutamate receptor 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 19 91.08 High High
Stress 71 89.76 High High
Shock 2 84.16 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

2 82.84 Quite High
Convulsion 1 80.76 Quite High
Apoptosis 1 78.60 Quite High
INFLAMMATION 1 78.04 Quite High
Pressure Volume 2 Under Development 2 71.60 Quite High
Aging 2 47.64 Quite Low
Intrauterine Growth Retardation 1 33.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The generated inventory of documented TFBS, recognized in the upstream 1,000 bp of the differentially expressed vs. non-differentially expressed genes, revealed that only binding sites of Elk-1 are significantly less associated with differential gene expression between WKY and SHR and between SHR+ATCE and SHR.
Elk-1 Binding (binding) of
1) Confidence 0.12 Published 2009 Journal Pflugers Arch Section Body Doc Link PMC2691531 Disease Relevance 0.29 Pain Relevance 0
P-CREB and P-Elk-1, by binding to these elements, enhance the transcription of the IEGs and regulate gene expression [25,26].
P-Elk-1 Binding (binding) of
2) Confidence 0.06 Published 2004 Journal BMC Neurosci Section Body Doc Link PMC526203 Disease Relevance 0.70 Pain Relevance 0.18

General Comments

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