INT179413

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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.97
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk8ip1) signal transduction (Mapk8ip1) mitochondrion (Mapk8ip1)
vesicle-mediated transport (Mapk8ip1) endoplasmic reticulum (Mapk8ip1) nucleus (Mapk8ip1)
Anatomy Link Frequency
brain 1
amygdala 1
Mapk8ip1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 24 99.68 Very High Very High Very High
Hippocampus 44 98.80 Very High Very High Very High
Visceral pain 4 58.76 Quite High
ischemia 2 58.16 Quite High
nMDA receptor 10 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
long-term potentiation 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 134 96.48 Very High Very High Very High
Shock 4 59.88 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

4 58.76 Quite High
Cv Unclassified Under Development 2 58.16 Quite High
Glioma 4 10.64 Low Low
Depression 8 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Depressive Disorder 2 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both P-JNK1 and P-JNK2/3 were significantly elevated in all brain areas, with the single exception of a non-significant increase in P-JNK1 in the amygdala (Fig. 4).
Positive_regulation (increase) of JNK1 in amygdala associated with amygdala
1) Confidence 0.01 Published 2004 Journal BMC Neurosci Section Body Doc Link PMC526203 Disease Relevance 0.38 Pain Relevance 0.14
P-JNK levels (P-JNK1 and/or P-JNK2/3) were increased in all brain regions about 2–5-fold, whereas P-p38MAPK levels remained essentially unchanged.
Positive_regulation (increased) of JNK1 in brain
2) Confidence 0.01 Published 2004 Journal BMC Neurosci Section Abstract Doc Link PMC526203 Disease Relevance 0.53 Pain Relevance 0.26

General Comments

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