INT179431

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Context Info
Confidence 0.78
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 2.34
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (AICDA) cytoplasm (AICDA)
Anatomy Link Frequency
edge 2
platelets 1
mere 1
AICDA (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 3 98.72 Very High Very High Very High
Inflammation 8 96.32 Very High Very High Very High
corticosteroid 6 50.00 Quite Low
agonist 24 36.28 Quite Low
palliative 1 20.12 Low Low
fibrosis 6 5.00 Very Low Very Low Very Low
Analgesic 4 5.00 Very Low Very Low Very Low
Buprenorphine 4 5.00 Very Low Very Low Very Low
cerebral cortex 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 4 99.68 Very High Very High Very High
Systemic Lupus Erythematosus 9 99.16 Very High Very High Very High
Rheumatoid Arthritis 18 98.72 Very High Very High Very High
Myositis 6 96.32 Very High Very High Very High
Pneumocystis Pneumonia 84 95.56 Very High Very High Very High
Vasculitis 4 95.16 Very High Very High Very High
Systemic Sclerosis 3 93.96 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 44 84.36 Quite High
Shock 4 76.68 Quite High
Disseminated Intravascular Coagulation 4 66.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Arp2/3 complex in these platelets, as identified using an antibody to the 34 kDa subunit, was localized primarily to the actin foci and to the cytoplasm.
Localization (localized) of Arp2 in platelets
1) Confidence 0.78 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC2203996 Disease Relevance 0.09 Pain Relevance 0
Immunolocalization of F-actin, Arp2/3 complex and cortactin was carried out as follows.
Localization (Immunolocalization) of Arp2
2) Confidence 0.73 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC2203996 Disease Relevance 0.07 Pain Relevance 0
When platelets were spread on fibrinogen in the presence of thrombin, cells from both genotypes contained actin-rich stress fibers and the Arp2/3 complex was localized predominantly to the peripheral edge of the lamella (Figure 2C) although some foci of Arp2/3 were also observed in the cytoplasm.
Localization (localized) of Arp2 in edge associated with stress
3) Confidence 0.68 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC2203996 Disease Relevance 0.10 Pain Relevance 0
When platelets were spread on fibrinogen in the presence of thrombin, cells from both genotypes contained actin-rich stress fibers and the Arp2/3 complex was localized predominantly to the peripheral edge of the lamella (Figure 2C) although some foci of Arp2/3 were also observed in the cytoplasm.
Localization (localized) of Arp2 in edge associated with stress
4) Confidence 0.68 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC2203996 Disease Relevance 0.10 Pain Relevance 0
What changes are needed in the global aid architecture and how can they be implemented?
Localization (architecture) of aid
5) Confidence 0.31 Published 2010 Journal Health Res Policy Syst Section Body Doc Link PMC2901220 Disease Relevance 0.08 Pain Relevance 0
They found the underlying AID in this group to be SLE (42%), rheumatoid arthritis (18%), Wegener's granulomatosis (14%), inflammatory myopathy (12%), polyarteritis nodosa (9%) and systemic sclerosis (5%).
Localization (found) of AID associated with inflammation, rheumatoid arthritis, systemic sclerosis, vasculitis and systemic lupus erythematosus
6) Confidence 0.05 Published 2004 Journal BMC Infect Dis Section Body Doc Link PMC526257 Disease Relevance 1.91 Pain Relevance 0.16
At first glance it appears that environmental inputs cannot meaningfully contribute to the integrated information generated by X, however this is not the case.
Localization (generated) of integrated
7) Confidence 0.04 Published 2008 Journal PLoS Computational Biology Section Body Doc Link PMC2386970 Disease Relevance 0 Pain Relevance 0
What we need to know, instead, is how much information is generated by the system as a whole, over and above the information generated independently by its parts, that is, we need to measure integrated information.
Localization (measure) of integrated
8) Confidence 0.04 Published 2008 Journal PLoS Computational Biology Section Body Doc Link PMC2386970 Disease Relevance 0 Pain Relevance 0
For instance, a system composed of causally interacting elements can generate large amounts of integrated information, while a mere copy or “replay” of its surface dynamics generates none.
Localization (amounts) of integrated in mere
9) Confidence 0.04 Published 2008 Journal PLoS Computational Biology Section Body Doc Link PMC2386970 Disease Relevance 0 Pain Relevance 0

General Comments

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