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Context Info
Confidence 0.05
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.79
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Trhde) cellular_component (Trhde) biological_process (Trhde)
Trhde (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 9 98.26 Very High Very High Very High
Inflammation 24 98.06 Very High Very High Very High
glial activation 1 96.60 Very High Very High Very High
cINOD 51 86.64 High High
COX-2 inhibitor 3 80.36 Quite High
metalloproteinase 12 76.44 Quite High
chemokine 1 67.52 Quite High
cva 7 63.32 Quite High
Inflammatory mediators 2 60.64 Quite High
Paracetamol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 31 98.06 Very High Very High Very High
Adhesions 2 94.96 High High
Amyloid Plaque 2 94.96 High High
Disease Progression 1 92.40 High High
Disease 34 91.52 High High
Aneurism 21 89.12 High High
Apoptosis 18 83.52 Quite High
Coronary Aneurysm 16 72.48 Quite High
Wound Healing 15 66.64 Quite High
Abdominal Aortic Aneurysm 3 63.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Genes regulated by ALR include ECM-degrading enzyme, heparanase, uPA/PL, BH-protocadherin, L1CAM, ALCAM and Keratin17, consistent with decreased expression of these molecules.
Gene_expression (include) of ECM-degrading enzyme
1) Confidence 0.05 Published 2008 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2254332 Disease Relevance 0.36 Pain Relevance 0.03
deposits (through release of insulin degrading enzyme, IDE), forming a protective barrier between A?
Gene_expression (through) of degrading enzyme
2) Confidence 0.04 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2893374 Disease Relevance 0.69 Pain Relevance 0.51
Similarly, measurement of locally produced inflammatory cytokines, hormones and growth factors would be interesting to know about, since these regulate matrix-degrading enzyme expression [16-19].
Gene_expression (expression) of matrix-degrading enzyme associated with inflammation and cytokine
3) Confidence 0.01 Published 2004 Journal Curr Control Trials Cardiovasc Med Section Body Doc Link PMC526392 Disease Relevance 0.74 Pain Relevance 0.34

General Comments

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