INT179491

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Context Info
Confidence 0.51
First Reported 2004
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 0.98
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Adipoq) extracellular region (Adipoq) endoplasmic reticulum (Adipoq)
Anatomy Link Frequency
fat 1
uterus 1
Adipoq (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 72 98.78 Very High Very High Very High
Potency 19 78.08 Quite High
antagonist 4 44.56 Quite Low
tolerance 10 38.60 Quite Low
anesthesia 3 29.20 Quite Low
cINOD 2 7.04 Low Low
Inflammation 23 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 1 96.60 Very High Very High Very High
Obesity 35 89.52 High High
Insulin Resistance 22 86.80 High High
Metabolic Syndrome 17 75.72 Quite High
Diabetes Mellitus 17 74.56 Quite High
Sleep Disorders 12 73.24 Quite High
Impaired Glucose Tolerance 10 38.60 Quite Low
INFLAMMATION 28 6.64 Low Low
Body Weight 16 5.00 Very Low Very Low Very Low
Hyperglycemia 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and glucocorticoids decrease adiponectin gene transcription [60-62].
Transcription (transcription) of adiponectin
1) Confidence 0.51 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2613381 Disease Relevance 0.45 Pain Relevance 0
To investigate the regulation of various genes in the uterus of rats during estrous cycle, the expression levels of CaBP-9k, oxytocin, Acrp30, Ldha, and S100a6 mRNA were analyzed by real-time PCR.
Spec (analyzed) Transcription (levels) of Acrp30 in uterus
2) Confidence 0.43 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1594574 Disease Relevance 0 Pain Relevance 0
agonists GI262570, GW347845, and pioglitazone significantly elevated serum adiponectin levels, increased adipose transcription of the PPAR?
Transcription (transcription) of serum adiponectin associated with agonist
3) Confidence 0.42 Published 2004 Journal BMC Pharmacol Section Body Doc Link PMC526775 Disease Relevance 0.25 Pain Relevance 0.28
Furthermore, expression of the UCP-2 and adiponectin mRNAs in the epididymal fat were higher in the Inslow group than the SF group, and were stimulated by a concomitant increase of the PPAR-?
Transcription (expression) of adiponectin in fat
4) Confidence 0.32 Published 2007 Journal Journal of Clinical Biochemistry and Nutrition Section Abstract Doc Link PMC2275770 Disease Relevance 0.28 Pain Relevance 0
protein was efficiently overexpressed (Fig. 4c), and that the level of adiponectin mRNA was enhanced by 15d-PGJ2 or rosiglitazone (Fig. 4d), in cells transfected with the PPAR?
Transcription (level) of adiponectin mRNA
5) Confidence 0.23 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297580 Disease Relevance 0 Pain Relevance 0.04

General Comments

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