INT179504

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Context Info
Confidence 0.07
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4, Myd88) plasma membrane (Tlr4, Myd88) intracellular (Tlr4, Myd88)
cytoplasm (Tlr4, Myd88) cytosol (Myd88) protein complex (Myd88)
Anatomy Link Frequency
neurons 1
Tlr4 (Mus musculus)
Myd88 (Mus musculus)
Pain Link Frequency Relevance Heat
Intracerebroventricular 29 85.28 High High
cytokine 4 19.20 Low Low
Pyramidal cell 7 11.68 Low Low
cINOD 10 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 17 80.08 Quite High
Stress 7 56.08 Quite High
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Dementia 5 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 3 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, these data strongly imply that LPS-activated microglial-mediated paracrine oxidative damage to neurons in vivo is dependent on CD14, MyD88, p50 of NF-?
LPS Regulation (dependent) of MyD88 in neurons
1) Confidence 0.07 Published 2004 Journal J Neuroinflammation Section Body Doc Link PMC527876 Disease Relevance 0.29 Pain Relevance 0.17

General Comments

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