INT179549

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Context Info
Confidence 0.19
First Reported 2004
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.36
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (C4b) extracellular region (C4b)
Anatomy Link Frequency
hippocampus 2
C4b (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 23 98.72 Very High Very High Very High
Hippocampus 25 98.54 Very High Very High Very High
Deafferentation 1 67.00 Quite High
Somatosensory cortex 1 37.68 Quite Low
Inflammation 12 35.28 Quite Low
cerebral cortex 6 27.68 Quite Low
Nerve growth factor 7 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
amygdala 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 16 100.00 Very High Very High Very High
Cv Unclassified Under Development 17 98.72 Very High Very High Very High
Neurodegenerative Disease 2 92.32 High High
Stress 15 89.76 High High
Disease 91 89.04 High High
Injury 7 84.16 Quite High
Scrapie 1 75.92 Quite High
Drug Induced Neurotoxicity 3 72.00 Quite High
Gliosis 2 54.00 Quite High
Apoptosis 4 51.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we subjected transgenic C4/?
Positive_regulation (transgenic) of Gene_expression (transgenic) of C4 associated with targeted disruption
1) Confidence 0.19 Published 2007 Journal Brain Pathology (Zurich, Switzerland) Section Body Doc Link PMC1859984 Disease Relevance 0.78 Pain Relevance 0.16
Colchicine infusion into the dorsal hippocampus, which selectively damages granule cells of the dentate gyrus, produced elevated mRNA expression of hippocampal C1qB and C4 [109].
Positive_regulation (elevated) of Gene_expression (expression) of C4 in hippocampus associated with hippocampus
2) Confidence 0.08 Published 2004 Journal J Neuroinflammation Section Body Doc Link PMC529311 Disease Relevance 0.58 Pain Relevance 0.33

General Comments

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