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Context Info
Confidence 0.82
First Reported 1975
Last Reported 1975
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrna7) plasma membrane (Chrna7) cytoplasm (Chrna7)
Anatomy Link Frequency
nucleus 1
Chrna7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Potency 1 92.28 High High
tetrodotoxin 1 78.80 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For maximal depolarizing activity, a substituted pyrrole moiety is necessary at the 20alpha-position of BTX-A and 3alpha, 9alpha-hemiketal linkage must remain intact providing rigidity for the pentacyclic steroid nucleus.
Phosphorylation (20alpha-position) of BTX in nucleus
1) Confidence 0.82 Published 1975 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 237113 Disease Relevance 0 Pain Relevance 0.12

General Comments

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