INT179671

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Context Info
Confidence 0.31
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 5.32
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Eln) extracellular region (Eln) proteinaceous extracellular matrix (Eln)
extracellular matrix organization (Eln)
Anatomy Link Frequency
extracellular matrix 2
blood vessels 1
body 1
Eln (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 50 96.12 Very High Very High Very High
cva 3 79.20 Quite High
metalloproteinase 11 61.68 Quite High
cytokine 11 5.00 Very Low Very Low Very Low
corticosteroid 9 5.00 Very Low Very Low Very Low
ketamine 6 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 162 99.68 Very High Very High Very High
Foreign Bodies 8 99.08 Very High Very High Very High
Emphysema 54 98.12 Very High Very High Very High
INFLAMMATION 56 96.12 Very High Very High Very High
Contracture 24 92.64 High High
Hyperplasia 16 87.44 High High
Adhesions 13 87.12 High High
Calcification 4 86.56 High High
Targeted Disruption 8 83.36 Quite High
Cancer 245 82.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A “blinded” pathologist (A.K.V.) evaluated all samples histologically for depth and length of the healed wound area, epithelial stratification, incorporation of the dermal substitute, degree of neutrophil, macrophage, fibroblast, and foreign body giant (FBG) cell infiltration, and extent of elastin formation.
elastin Binding (formation) of in body associated with injury and foreign bodies
1) Confidence 0.31 Published 2005 Journal Journal of Burns and Wounds Section Body Doc Link PMC1501115 Disease Relevance 0.75 Pain Relevance 0
Although the Dermalogen group had the thickest elastin fiber fragments, Dermagraft may have initiated the earliest elastin fiber formation in the wounds.
elastin Binding (formation) of associated with injury
2) Confidence 0.30 Published 2005 Journal Journal of Burns and Wounds Section Abstract Doc Link PMC1501115 Disease Relevance 1.28 Pain Relevance 0
Fibulin-2 has been observed in coronary arteries and the aortic arch, binding to elastin and fibrillin-1 [4], but fibulins-3 and 6 have not been seen in large blood vessels.
elastin Binding (binding) of in blood vessels
3) Confidence 0.18 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1794134 Disease Relevance 0.29 Pain Relevance 0.04
Addition of lathyrogen beta-aminopropionile leads to an impairment of collagen and elastin crosslinking and therefore further increases the extent of emphysema-like lesions [158].
elastin Binding (crosslinking) of associated with emphysema
4) Confidence 0.04 Published 2004 Journal Respir Res Section Body Doc Link PMC533858 Disease Relevance 0.93 Pain Relevance 0.13
LOX, a copper-dependent amine oxidase, was initially reported as responsible for the catalysis of collagen and elastin cross-linking within the extracellular matrix [40].
elastin Binding (linking) of in extracellular matrix
5) Confidence 0.04 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2922193 Disease Relevance 1.04 Pain Relevance 0.03
LOX, a copper-dependent amine oxidase, was initially reported as responsible for the catalysis of collagen and elastin cross-linking within the extracellular matrix [40].
elastin Binding (cross) of in extracellular matrix
6) Confidence 0.04 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2922193 Disease Relevance 1.04 Pain Relevance 0.03

General Comments

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