INT179683

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Context Info
Confidence 0.00
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.02
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Col7a1, Eln) proteinaceous extracellular matrix (Col7a1, Eln) mitochondrion (Eln)
cell adhesion (Col7a1) extracellular matrix organization (Eln)
Anatomy Link Frequency
extracellular matrix 2
Col7a1 (Mus musculus)
Eln (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 50 96.64 Very High Very High Very High
metalloproteinase 11 61.68 Quite High
cytokine 11 5.00 Very Low Very Low Very Low
corticosteroid 9 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Emphysema 54 98.12 Very High Very High Very High
INFLAMMATION 56 96.64 Very High Very High Very High
Injury 6 88.00 High High
Adhesions 13 87.64 High High
Cancer 245 82.08 Quite High
Metastasis 100 70.96 Quite High
Apoptosis 25 69.12 Quite High
Pulmonary Disease 146 68.64 Quite High
Head & Neck Cancer 12 50.00 Quite Low
Metaplasia 4 42.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LOX, a copper-dependent amine oxidase, was initially reported as responsible for the catalysis of collagen and elastin cross-linking within the extracellular matrix [40].
collagen Binding (cross) of elastin in extracellular matrix
1) Confidence 0.00 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2922193 Disease Relevance 1.04 Pain Relevance 0.03
LOX, a copper-dependent amine oxidase, was initially reported as responsible for the catalysis of collagen and elastin cross-linking within the extracellular matrix [40].
collagen Binding (linking) of elastin in extracellular matrix
2) Confidence 0.00 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2922193 Disease Relevance 1.04 Pain Relevance 0.03
Addition of lathyrogen beta-aminopropionile leads to an impairment of collagen and elastin crosslinking and therefore further increases the extent of emphysema-like lesions [158].
collagen Binding (crosslinking) of elastin associated with emphysema
3) Confidence 0.00 Published 2004 Journal Respir Res Section Body Doc Link PMC533858 Disease Relevance 0.93 Pain Relevance 0.13

General Comments

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