INT179790

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Context Info
Confidence 0.10
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ecm1) extracellular space (Ecm1) extracellular region (Ecm1)
proteinaceous extracellular matrix (Ecm1) enzyme binding (Ecm1) signal transducer activity (Ecm1)
Ecm1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 12 98.82 Very High Very High Very High
metalloproteinase 20 51.44 Quite High
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Reprotox - General 3 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low
Hemorrhage 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To confirm the altered mRNA expression of the ECM genes COL3A1, SPARC, BGN and NID1 at 48 h of decidualization, quantitative real-time RT-PCR was carried out using the same RNA samples used in the microarray analysis, plus two additional RNA samples of each genotype, collected in the same way.
Transcription (expression) of ECM
1) Confidence 0.10 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC535545 Disease Relevance 0 Pain Relevance 0
Given that IL-11 is a secreted cytokine with autocrine and paracrine activity, a direct effect on ECM molecule transcription would be dependent on coincident expression patterns of the ECM molecules, IL-11 and its receptors.
Transcription (transcription) of ECM associated with cytokine
2) Confidence 0.09 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC535545 Disease Relevance 0 Pain Relevance 0.08

General Comments

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