INT179823

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.78
First Reported 2004
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 13
Total Number 13
Disease Relevance 2.18
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il11) extracellular region (Il11) cytoplasm (Il11)
Anatomy Link Frequency
endometrium 1
decidua 1
parathyroid 1
Il11 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 115 100.00 Very High Very High Very High
palliative 2 90.56 High High
Pain 18 80.16 Quite High
visual analogue scale 6 77.80 Quite High
metalloproteinase 38 62.04 Quite High
Inflammation 4 60.40 Quite High
rheumatoid arthritis 41 56.80 Quite High
Arthritis 2 50.00 Quite Low
cva 2 20.64 Low Low
ketamine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 34 99.48 Very High Very High Very High
Osteoporosis 13 99.00 Very High Very High Very High
Disease 29 94.96 High High
Metastasis 106 88.00 High High
Cancer 130 86.80 High High
Hypercalcemia 10 81.60 Quite High
Spontaneous Fractures 2 81.00 Quite High
Pain 18 80.16 Quite High
Hypoxia 77 75.36 Quite High
Pressure And Volume Under Development 1 71.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have also shown co-localization of IL-11, IL-11R?
Localization (localization) of IL-11
1) Confidence 0.78 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0 Pain Relevance 0.04
However, we saw no co-localization between IL-11R?
Localization (localization) of IL-11
2) Confidence 0.78 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0 Pain Relevance 0.03
Subsequently, we investigated the co-localization of IL-11 (green channel), IL-11R?
Localization (localization) of IL-11
3) Confidence 0.73 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0 Pain Relevance 0
Subsequently, we have shown that both IL-11 and GP130 mRNA expression are elevated in the late secretory phase of the menstrual cycle whereas IL-11R?
Localization (secretory) of IL-11
4) Confidence 0.73 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0 Pain Relevance 0.06
IL-11 is a secreted cytokine which is known to signal via its receptors, IL-11R?
Localization (secreted) of IL-11 associated with cytokine
5) Confidence 0.73 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0 Pain Relevance 0.05
In late secretory phase endometrium and first trimester decidua IL-11, IL-11R?
Localization (secretory) of IL-11 in decidua
6) Confidence 0.73 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0 Pain Relevance 0
However, we found no co-localization between IL-11R?
Localization (localization) of IL-11
7) Confidence 0.73 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0 Pain Relevance 0
Finally, we have shown the potential for both autocrine and paracrine signalling in the human endometrium by co-localizing IL-11, IL-11R?
Localization (localizing) of IL-11 in endometrium
8) Confidence 0.68 Published 2010 Journal Molecular Human Reproduction Section Abstract Doc Link PMC2816169 Disease Relevance 0 Pain Relevance 0.03
Localization of IL-11R?
Localization (Localization) of IL-11
9) Confidence 0.68 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0.06 Pain Relevance 0
Measurement of IL-6, IL-11 and LIF levels
Localization (Measurement) of IL-11
10) Confidence 0.48 Published 2011 Journal Yonsei Medical Journal Section Body Doc Link PMC3017685 Disease Relevance 0.66 Pain Relevance 0.38
Given that IL-11 is a secreted cytokine with autocrine and paracrine activity, a direct effect on ECM molecule transcription would be dependent on coincident expression patterns of the ECM molecules, IL-11 and its receptors.
Localization (secreted) of IL-11 associated with cytokine
11) Confidence 0.40 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC535545 Disease Relevance 0 Pain Relevance 0.05
Localization and expression of IL-11, IL-11R?
Localization (Localization) of IL-11
12) Confidence 0.38 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC535545 Disease Relevance 0.06 Pain Relevance 0.14
Breast cancers that metastasize to bone secrete factors, such as parathyroid hormone-related protein (PTHrP) and interleukin-11 (IL-11), that stimulate osteoclastic bone destruction and the release and activation of growth factors immobilized in the bone matrix.
Localization (secrete) of interleukin-11 in parathyroid associated with breast cancer and osteoporosis
13) Confidence 0.29 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2731927 Disease Relevance 1.39 Pain Relevance 0.17

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox