INT179830

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.41
First Reported 2004
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 7
Disease Relevance 2.87
Pain Relevance 1.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il11) extracellular region (Il11) cytoplasm (Il11)
Anatomy Link Frequency
decidua 2
Il11 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 196 98.70 Very High Very High Very High
rheumatoid arthritis 123 92.64 High High
Inflammation 12 89.00 High High
metalloproteinase 24 88.88 High High
Inflammatory response 18 87.16 High High
Arthritis 6 75.00 Quite High
Pain 20 5.00 Very Low Very Low Very Low
visual analogue scale 18 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 3 4 98.76 Very High Very High Very High
Disease 87 98.70 Very High Very High Very High
Rheumatoid Arthritis 126 92.64 High High
INFLAMMATION 30 89.00 High High
Down Syndrome 2 81.76 Quite High
Leukemia 10 76.84 Quite High
Infection 6 68.96 Quite High
Arthropathy 6 67.36 Quite High
Arthritis 3 18.88 Low Low
Pain 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment of first trimester decidua with 40 nM PROK1 had no effect on expression levels of IL-11R?
Negative_regulation (levels) of IL-11 in decidua
1) Confidence 0.41 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0.07 Pain Relevance 0
Treatment of PROKR1 Ishikawa cells with 40 nM PROK1 had no effect on expression levels of IL-11R?
Negative_regulation (levels) of IL-11
2) Confidence 0.41 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0.08 Pain Relevance 0
Plasma levels of IL-11 are decreased in women with first trimester spontaneous abortion [22], and there is decreased expression of IL-11 protein in chorionic villi and decidua from anembryonic compared to normal pregnancy [23].
Negative_regulation (decreased) of IL-11 in decidua associated with reprotox - general 3
3) Confidence 0.29 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC535545 Disease Relevance 0.10 Pain Relevance 0.04
In this study, IL-6 and IL-11 levels decreased by treatment, but the level of LIF did not.
Negative_regulation (decreased) of IL-11
4) Confidence 0.28 Published 2011 Journal Yonsei Medical Journal Section Body Doc Link PMC3017685 Disease Relevance 0.79 Pain Relevance 0.55
After eight weeks of medical treatment in patients with high disease activity, a decrease in DAS28 was associated with a significant decrease in the serum concentrations of IL-6 and IL-11.


Negative_regulation (decrease) of IL-11 associated with disease
5) Confidence 0.28 Published 2011 Journal Yonsei Medical Journal Section Abstract Doc Link PMC3017685 Disease Relevance 1.00 Pain Relevance 0.47
We further investigated whether IL-6 family cytokines levels can change and found that the concentrations of IL-6 and IL-11 significantly decreased as DAS28 decreased (Table 4).
Negative_regulation (decreased) of IL-11 associated with cytokine
6) Confidence 0.27 Published 2011 Journal Yonsei Medical Journal Section Body Doc Link PMC3017685 Disease Relevance 0.83 Pain Relevance 0.54
Dysregulation of collagen III, biglycan, nidogen-1 and SPARC in the absence of IL-11 signaling at the time of decidualization may indicate essential functions for these molecules during the implantation process in mice.
Negative_regulation (absence) of IL-11
7) Confidence 0.21 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC535545 Disease Relevance 0 Pain Relevance 0.28

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox