INT179833

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Context Info
Confidence 0.44
First Reported 2004
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.08
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il11) extracellular region (Il11) cytoplasm (Il11)
Il11 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 16 98.10 Very High Very High Very High
metalloproteinase 14 57.92 Quite High
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Down Syndrome 2 81.76 Quite High
Infection 6 5.00 Very Low Very Low Very Low
Adhesions 5 5.00 Very Low Very Low Very Low
Leukemia 3 5.00 Very Low Very Low Very Low
Reprotox - General 3 3 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Female Infertility 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and GP130; hence we investigated the potential for autocrine or paracrine signalling by localizing the sites of protein expression of GP130, IL-11R?
Spec (investigated) Regulation (sites) of Gene_expression (expression) of IL-11
1) Confidence 0.44 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0 Pain Relevance 0.05
Treatment of PROKR1 Ishikawa cells with 40 nM PROK1 had no effect on expression levels of IL-11R?
Neg (no) Regulation (effect) of Gene_expression (expression) of IL-11
2) Confidence 0.26 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0.08 Pain Relevance 0
Given that IL-11 is a secreted cytokine with autocrine and paracrine activity, a direct effect on ECM molecule transcription would be dependent on coincident expression patterns of the ECM molecules, IL-11 and its receptors.
Regulation (dependent) of Gene_expression (expression) of IL-11 associated with cytokine
3) Confidence 0.23 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC535545 Disease Relevance 0 Pain Relevance 0.11

General Comments

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