INT179863

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Context Info
Confidence 0.00
First Reported 2004
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.71
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
Paw 1
HIST2H2AA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 54 99.28 Very High Very High Very High
Inflammatory mediators 29 97.00 Very High Very High Very High
cytokine 28 87.24 High High
Inflammation 84 82.72 Quite High
antagonist 36 5.00 Very Low Very Low Very Low
calcitonin gene related peptide 32 5.00 Very Low Very Low Very Low
chemokine 18 5.00 Very Low Very Low Very Low
qutenza 12 5.00 Very Low Very Low Very Low
tetrodotoxin 6 5.00 Very Low Very Low Very Low
TRP channel 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 62 98.92 Very High Very High Very High
INFLAMMATION 105 97.00 Very High Very High Very High
Esophageal Disease 44 68.84 Quite High
Injury 23 62.64 Quite High
Muscle Hypertonia 2 28.04 Quite Low
Adult Respiratory Distress Syndrome 30 5.00 Very Low Very Low Very Low
Gastroesophageal Reflux Disease 24 5.00 Very Low Very Low Very Low
Lung Injury 17 5.00 Very Low Very Low Very Low
Acid Reflux 6 5.00 Very Low Very Low Very Low
Shock 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
H2O2 may also interact with DNA bases (more than 20 different oxidatively altered purines and pyrimidines have been detected and characterized),86 perhaps inducing alterations of cell phenotype and possibly resulting in permanent mutations.
H2O2 Binding (interact) of
1) Confidence 0.00 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2978390 Disease Relevance 0.43 Pain Relevance 0.32
H2O2 is uncharged, freely diffusible through cellular membranes, and likely to interact with membrane lipids, causing lipid peroxidation and peroxidation-induced inflammatory mediators.
H2O2 Spec (likely) Binding (interact) of associated with inflammatory mediators
2) Confidence 0.00 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2978390 Disease Relevance 0.60 Pain Relevance 0.36
A group × time interaction for mean Paw was seen (p = 0.002) with Paw lowest with BVV (Paw at 5 hr was 14.3 ± 0.4 cm H2O with BVV; 15.1 ± 0.2 with CMV-RM and 15.1 ± 1.0 with CMV respectively).
H2O Binding (interaction) of in Paw associated with cytomegalovirus infection
3) Confidence 0.00 Published 2004 Journal Respir Res Section Body Doc Link PMC535805 Disease Relevance 0.68 Pain Relevance 0

General Comments

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