INT179888

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Context Info
Confidence 0.39
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.85
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (KRT7) nucleolus (KRT7) structural molecule activity (KRT7)
nucleus (KRT7) cytoskeleton organization (KRT7) cytoplasm (KRT7)
Anatomy Link Frequency
liver 1
KRT7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 1 99.68 Very High Very High Very High
imagery 3 58.64 Quite High
backache 4 57.52 Quite High
Inflammation 4 28.08 Quite Low
Pain 2 25.48 Quite Low
endometriosis 1 23.04 Low Low
abdominal pain 1 18.76 Low Low
Spinal cord 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 50 99.30 Very High Very High Very High
Cyst 11 89.68 High High
Chordoma 18 89.52 High High
Carcinoma 30 89.00 High High
Ependymoma 74 88.12 High High
Pancreatic Cyst 1 80.80 Quite High
Metastasis 3 78.12 Quite High
Recurrence 5 77.56 Quite High
Glioma 8 68.64 Quite High
Necrosis 2 64.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HepPar1 staining shows throughout the liver tissue samples, whereas the CK7 is localized in the bile ducts.


Localization (localized) of CK7 in liver associated with bile
1) Confidence 0.39 Published 2004 Journal Comp Hepatol Section Body Doc Link PMC535891 Disease Relevance 0.06 Pain Relevance 0.05
The antigens tested by immunohistochemistry were: pan-keratin, keratin Cam 5.2, cytokeratin 7, cytokeratin 10, cytokeratin 18, cytokeratin 20, epithelial membrane antigen, vimentin, desmin, actin, myosin, CD34, CD68, CD99, CD117, S-100 protein, and bcl-2.
Localization (desmin) of cytokeratin 7
2) Confidence 0.32 Published 2007 Journal Virchows Arch Section Body Doc Link PMC2039817 Disease Relevance 0.56 Pain Relevance 0
The tumour cells in both cases showed strong positivity for cytokeratin markers, AE1AE3 (figure 5a), CAM 5.2 (figure 5b) and focally for cytokeratin 7.
Localization (positivity) of cytokeratin associated with cancer
3) Confidence 0.11 Published 2008 Journal Diagn Pathol Section Body Doc Link PMC2584038 Disease Relevance 1.07 Pain Relevance 0.09
The tumour cells in both cases showed strong positivity for cytokeratin markers, AE1AE3 (figure 5a), CAM 5.2 (figure 5b) and focally for cytokeratin 7.
Localization (positivity) of cytokeratin associated with cancer
4) Confidence 0.11 Published 2008 Journal Diagn Pathol Section Body Doc Link PMC2584038 Disease Relevance 1.15 Pain Relevance 0.09

General Comments

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