INT179931

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Context Info
Confidence 0.04
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ephb1) aging (Mmp9) extracellular matrix organization (Mmp9)
protein complex (Mmp9) cytoplasm (Ephb1) peptidase activity (Mmp9)
Anatomy Link Frequency
lung 2
Ephb1 (Rattus norvegicus)
Mmp9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 6 79.60 Quite High
Inflammation 13 79.20 Quite High
Inflammatory mediators 7 23.00 Low Low
metalloproteinase 29 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adult Respiratory Distress Syndrome 17 100.00 Very High Very High Very High
INFLAMMATION 18 79.20 Quite High
Stress 2 77.20 Quite High
Pulmonary Disease 2 61.28 Quite High
Body Weight 5 34.88 Quite Low
Lung Injury 13 21.48 Low Low
Injury 6 17.88 Low Low
Pneumonia 3 5.00 Very Low Very Low Very Low
Hyperoxia 2 5.00 Very Low Very Low Very Low
Ulcers 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, using a selective JNK inhibitor, SP600125, and the downstream MEK inhibitor of ERK, PD98059, we focused on the roles of JNK and ERK in LPS-induced acute lung injury and production of CINC, MMP-9, and NO.
ERK Regulation (roles) of Gene_expression (production) of MMP-9 in lung associated with adult respiratory distress syndrome
1) Confidence 0.04 Published 2004 Journal Respir Res Section Body Doc Link PMC538282 Disease Relevance 0.48 Pain Relevance 0.15

General Comments

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