INT18008

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.40
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.50
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL3) extracellular region (IL3) cell-cell signaling (IL3)
Anatomy Link Frequency
platelet 1
intestine 1
neutrophil 1
IL3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 35 100.00 Very High Very High Very High
chemokine 4 97.60 Very High Very High Very High
Inflammation 65 97.36 Very High Very High Very High
bradykinin 11 95.60 Very High Very High Very High
corticosteroid 2 76.80 Quite High
aspirin 2 66.96 Quite High
agonist 7 58.00 Quite High
Neuropeptide 1 40.32 Quite Low
substance P 4 39.28 Quite Low
headache 2 37.20 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 92 97.36 Very High Very High Very High
Cryptosporidiosis 1 96.80 Very High Very High Very High
Anti-phospholipid Antibody Syndrome 79 91.20 High High
Heart Failure 3 88.76 High High
Sepsis 60 86.60 High High
Malignant Neoplastic Disease 2 86.60 High High
Heparin-induced Thrombocytopenia 5 78.80 Quite High
Thrombosis 43 69.84 Quite High
Nicotine Addiction 1 63.24 Quite High
Hyperlipidemia 1 61.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A transient decrease of eosinophil and monocyte counts was observed immediately after IV injection of rhIL-3, whereas the neutrophil count remained unaffected.
Negative_regulation (injection) of rhIL-3 in neutrophil
1) Confidence 0.40 Published 1991 Journal J. Clin. Oncol. Section Abstract Doc Link 1960553 Disease Relevance 0.09 Pain Relevance 0
These options include ancrod, hirudin, lepirudin, argatroban, prostacyclin, platelet IIb/IIIa inhibitors, complement inhibitors, IL-3 and bivalirudin [56,72].
Negative_regulation (inhibitors) of IL-3 in platelet
2) Confidence 0.05 Published 2010 Journal J Cardiothorac Surg Section Body Doc Link PMC2987921 Disease Relevance 0.77 Pain Relevance 0.07
The PGE2 mediated effect of TNF and also of IL-1 beta and IL-3 in increase of intestinal chloride secretion was confirmed in studies in which cryptosporidium infected pig ileum and untreated chicken intestine was found to respond with increased short circuit current to these cytokines.
Negative_regulation (effect) of IL-3 in intestine associated with cryptosporidiosis and cytokine
3) Confidence 0.03 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1562419 Disease Relevance 0.30 Pain Relevance 0.18
On the cellular level, this action is mediated by the inhibition of the production and of the activity of proinflammatory cytokines (IL-1, IL-2, IL-3, IL-6, interferon-?
Negative_regulation (inhibition) of IL-3 associated with cytokine
4) Confidence 0.01 Published 2004 Journal Crit Care Section Body Doc Link PMC420022 Disease Relevance 0.35 Pain Relevance 0.37

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox