INT180149

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Context Info
Confidence 0.40
First Reported 2004
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 2.65
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SRA1) cell proliferation (SRA1) nucleus (SRA1)
DNA binding (SRA1) cytoplasm (SRA1)
Anatomy Link Frequency
hip 2
SRA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 69 96.84 Very High Very High Very High
Pain 35 90.88 High High
agonist 46 85.44 High High
Inflammation 15 6.00 Low Low
antagonist 49 5.00 Very Low Very Low Very Low
corticosteroid 10 5.00 Very Low Very Low Very Low
endometriosis 7 5.00 Very Low Very Low Very Low
dexamethasone 5 5.00 Very Low Very Low Very Low
cerebral cortex 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteophyte 2 99.00 Very High Very High Very High
Idiopathic Pulmonary Fibrosis 69 96.84 Very High Very High Very High
Osteoarthritis 2 96.04 Very High Very High Very High
Cancer 26 93.28 High High
Obesity 31 89.00 High High
Pain 31 84.44 Quite High
Hypertension 3 83.88 Quite High
Diabetes Mellitus 10 83.20 Quite High
Neuroblastoma 6 78.64 Quite High
Nicotine Addiction 9 76.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The patient elected to undergo hip SRA in late 2006.
Positive_regulation (undergo) of hip SRA in hip
1) Confidence 0.40 Published 2010 Journal Patient Saf Surg Section Body Doc Link PMC2829516 Disease Relevance 0.32 Pain Relevance 0.33
The patient elected to undergo hip SRA.
Positive_regulation (undergo) of hip SRA in hip
2) Confidence 0.40 Published 2010 Journal Patient Saf Surg Section Body Doc Link PMC2829516 Disease Relevance 1.01 Pain Relevance 0.08
Because the conditions needed to build complexes of high ?
Positive_regulation (build) of complexes
3) Confidence 0.05 Published 2004 Journal BMC Neurosci Section Body Doc Link PMC543470 Disease Relevance 0 Pain Relevance 0
expression can result in a reduced activity of cyclin/CDK complexes which
Positive_regulation (activity) of complexes
4) Confidence 0.03 Published 2008 Journal PPAR Research Section Body Doc Link PMC2443425 Disease Relevance 0.15 Pain Relevance 0
increase in Mad-1 binding complexes which could contribute to the switch from c-Myc/Max to Mad1/Max with repressor
Positive_regulation (increase) of complexes
5) Confidence 0.03 Published 2008 Journal PPAR Research Section Body Doc Link PMC2443425 Disease Relevance 0.21 Pain Relevance 0
Supraphysiological concentrations of estradiol and subtle progesterone rises in the late follicular phase might be responsible for this modulated steroid receptor profile.
Spec (might) Positive_regulation (responsible) of steroid receptor
6) Confidence 0.01 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1266397 Disease Relevance 0 Pain Relevance 0.04
All together, these synergistic functions of NRP1 in reducing anti-angiogenic complexes and promoting pro-angiogenic complexes, were in tune with computational predictions from our previous studies in the absence of sVEGFR1 [54].

3.2.

Positive_regulation (promoting) of complexes
7) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0 Pain Relevance 0
complexes were higher in the standard and non-reducing Western blots (4.6 and 5.1 fold) and the levels of Hb?
Positive_regulation (higher) of complexes
8) Confidence 0.01 Published 2010 Journal Respir Res Section Body Doc Link PMC2949726 Disease Relevance 0.96 Pain Relevance 0.20

General Comments

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