INT180191

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Context Info
Confidence 0.29
First Reported 2004
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.04
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B cells 2
PCS (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 2 67.64 Quite High
Duloxetine 42 50.00 Quite Low
Inflammation 4 45.08 Quite Low
headache 5 27.44 Quite Low
antidepressant 12 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
sSRI 6 5.00 Very Low Very Low Very Low
tricyclic antidepressant 4 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Weight Loss 6 100.00 Very High Very High Very High
Bacterial Infection 34 99.98 Very High Very High Very High
Systemic Lupus Erythematosus 126 98.76 Very High Very High Very High
Weight Gain 7 98.64 Very High Very High Very High
Disease 54 96.64 Very High Very High Very High
Congenital Anomalies 7 93.52 High High
Body Weight 4 91.28 High High
Opportunistic Infections 2 90.24 High High
Infection 8 76.32 Quite High
Depression 22 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, the presence of serum ANAs itself does not coincide with increased numbers of IgD+ CD38++ transitional B cells and CD27++ PCs as characteristically seen in SLE patients.
Positive_regulation (increased) of Negative_regulation (numbers) of PCs in B cells associated with systemic lupus erythematosus
1) Confidence 0.29 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.10 Pain Relevance 0
We found that patients with bacterial infections reached similar frequencies and absolute numbers of CD27++ PCs as previously reported in active SLE patients (12, 14).
Positive_regulation (reached) of Negative_regulation (numbers) of PCs associated with systemic lupus erythematosus and bacterial infection
2) Confidence 0.29 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 1.21 Pain Relevance 0.03
A total of 3/98 patients (3.1%) experienced PCS weight loss while 6/98 (6.1%) reported a PCS weight gain (PCS weight change is defined as a change of ?
Positive_regulation (experienced) of Negative_regulation (loss) of PCS associated with weight loss and weight gain
3) Confidence 0.03 Published 2004 Journal BMC Geriatr Section Body Doc Link PMC544561 Disease Relevance 0.73 Pain Relevance 0

General Comments

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