INT180234

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Context Info
Confidence 0.08
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.54
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Plp1)
Anatomy Link Frequency
frontal cortex 2
Plp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 17 99.88 Very High Very High Very High
gABA 29 98.92 Very High Very High Very High
GABA receptor 1 66.04 Quite High
imagery 4 62.48 Quite High
anesthesia 1 60.64 Quite High
cerebral cortex 2 54.08 Quite High
GABAergic 2 46.48 Quite Low
hyperexcitability 1 43.68 Quite Low
Transcranial magnetic stimulation 1 38.08 Quite Low
Neurotransmitter 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 99.68 Very High Very High Very High
Epilepsy 10 93.24 High High
Stiff-person Syndrome 2 90.32 High High
Syndrome 14 88.40 High High
Ataxia 5 86.32 High High
Tonic-clonic Epilepsy 1 85.88 High High
Cerebral Palsy 43 84.96 Quite High
Generalized Anxiety Disorder 17 82.76 Quite High
Convulsion 3 77.56 Quite High
Cleft Palate 4 69.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Decreased levels of brain and CSF GABA, increased levels of CSF and cortical glutamate, and decreased levels of PLP in the frontal cortex, have been described in this condition.
Negative_regulation (decreased) of Gene_expression (levels) of PLP in frontal cortex associated with glutamate, gaba and urological neuroanatomy
1) Confidence 0.08 Published 2004 Journal BMC Neurol Section Body Doc Link PMC544830 Disease Relevance 1.54 Pain Relevance 0.42

General Comments

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