INT180239

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Context Info
Confidence 0.42
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.59
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (Gad2) Golgi apparatus (Gad2) plasma membrane (Gad2)
cytoplasm (Gad2)
Gad2 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 30 98.76 Very High Very High Very High
Pyramidal cell 24 93.84 High High
Glutamate 17 88.28 High High
imagery 7 87.84 High High
GABAergic 4 71.84 Quite High
hyperexcitability 1 69.04 Quite High
Transcranial magnetic stimulation 1 63.44 Quite High
GABA receptor 1 54.56 Quite High
anesthesia 1 49.16 Quite Low
cerebral cortex 2 42.60 Quite Low
Disease Link Frequency Relevance Heat
Ataxia 5 96.96 Very High Very High Very High
Syndrome 14 95.36 Very High Very High Very High
Stiff-person Syndrome 2 95.12 Very High Very High Very High
Urological Neuroanatomy 1 90.32 High High
Epilepsy 10 81.76 Quite High
Muscle Rigidity 2 81.76 Quite High
Muscular Spasm 2 79.44 Quite High
Tonic-clonic Epilepsy 1 74.40 Quite High
Cerebral Palsy 43 73.48 Quite High
Generalized Anxiety Disorder 18 71.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mower and Guo (2001) reported approximately 30 GAD65 positive puncta per 400 ?
Negative_regulation (reported) of Gene_expression (puncta) of GAD65
1) Confidence 0.42 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2686200 Disease Relevance 0 Pain Relevance 0.09
GABA-mediated synaptic transmission is thought to be functionally impaired by the production of autoantibodies to GAD65 and GAD67 [35-37].
Negative_regulation (impaired) of Gene_expression (production) of GAD65 associated with gaba
2) Confidence 0.35 Published 2004 Journal BMC Neurol Section Body Doc Link PMC544830 Disease Relevance 1.59 Pain Relevance 0.46

General Comments

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