INT180359

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Context Info
Confidence 0.54
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.94
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

histone binding (AIRE) nucleolus (AIRE) plasma membrane (AIRE)
nucleus (AIRE) DNA binding (AIRE) cytoplasm (AIRE)
AIRE (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 4 61.76 Quite High
alcohol 2 21.12 Low Low
Inflammation 8 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 47 100.00 Very High Very High Very High
Hypocalcemia 4 99.56 Very High Very High Very High
Autoimmune Hepatitis 338 99.24 Very High Very High Very High
Hypopigmentation 5 98.92 Very High Very High Very High
Disease 123 98.44 Very High Very High Very High
Hepatitis 36 97.36 Very High Very High Very High
Premature Menopause 1 95.76 Very High Very High Very High
Liver Disease 18 95.52 Very High Very High Very High
Premature Ovarian Failure 6 91.96 High High
Primary Sclerosing Cholangitis 14 89.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The patients with hypoparathyroidism as the first sign of autoimmune disease should be classified as APS1, with different genetic background as compared with our other patients from the APS2 group.
Localization (disease) of autoimmune associated with hypocalcemia and autoimmune disease
1) Confidence 0.54 Published 2010 Journal Autoimmune Diseases Section Body Doc Link PMC3005832 Disease Relevance 1.69 Pain Relevance 0
So far, anti-AADC autoantibodies have only been reported in APECED and their role in AIH and vitiligo as disease components of APECED deserve further investigation.

6.

Localization (reported) of APECED associated with autoimmune hepatitis, hypopigmentation and disease
2) Confidence 0.10 Published 2004 Journal J Autoimmune Dis Section Body Doc Link PMC544946 Disease Relevance 1.16 Pain Relevance 0
In APECED, autoantibodies are directed against specific cytochrome P450 enzymes (e.g.
Localization (directed) of APECED
3) Confidence 0.10 Published 2004 Journal J Autoimmune Dis Section Body Doc Link PMC544946 Disease Relevance 1.09 Pain Relevance 0.03

General Comments

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