INT180360

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Context Info
Confidence 0.45
First Reported 2004
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (ENAM) proteinaceous extracellular matrix (ENAM)
ENAM (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 4 35.28 Quite Low
alcohol 2 33.64 Quite Low
Inflammation 8 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Hepatitis 338 100.00 Very High Very High Very High
Primary Sclerosing Cholangitis 14 99.12 Very High Very High Very High
Amelogenesis Imperfecta 81 97.68 Very High Very High Very High
Disease 81 96.24 Very High Very High Very High
Liver Disease 18 86.32 High High
Hypocalcemia 2 80.76 Quite High
Autoimmune Disease 20 77.16 Quite High
Candida Infection 6 76.24 Quite High
Syndrome 19 74.08 Quite High
Polyglandular Deficiency Syndrome 4 71.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The albumin ALB, ameloblastin AMBN and enamelin ENAM genes all map to the same region and are therefore candidate genes for autosomal AI.
Gene_expression (genes) of enamelin associated with amelogenesis imperfecta
1) Confidence 0.45 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1853073 Disease Relevance 0.67 Pain Relevance 0
Apart from serological differences, AIH-2 seems to be clinically and genetically distinguishable from AIH-1 [5,8,14].
Spec (seems) Gene_expression (seems) of AIH-2 associated with autoimmune hepatitis
2) Confidence 0.09 Published 2004 Journal J Autoimmune Dis Section Body Doc Link PMC544946 Disease Relevance 1.86 Pain Relevance 0
However, a recent study has shown that anti-SLA/LP autoantibodies can also be detected in AIH-2 and in children with PSC.
Gene_expression (detected) of AIH-2 associated with autoimmune hepatitis and primary sclerosing cholangitis
3) Confidence 0.09 Published 2004 Journal J Autoimmune Dis Section Body Doc Link PMC544946 Disease Relevance 1.06 Pain Relevance 0

General Comments

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