INT180373

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Context Info
Confidence 0.05
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.01
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (CYP2A6, Cyp2d4) mitochondrion (Cyp2d4) oxidoreductase activity (Cyp2d4)
small molecule metabolic process (CYP2A6) enzyme binding (CYP2A6) cellular_component (Cyp2d4)
CYP2A6 (Homo sapiens)
Cyp2d4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tolerance 2 95.88 Very High Very High Very High
Inflammation 4 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Hepatitis 169 100.00 Very High Very High Very High
Hepatitis C Virus Infection 43 100.00 Very High Very High Very High
Hepatitis 18 100.00 Very High Very High Very High
Infection 17 100.00 Very High Very High Very High
Chronic Hepatitis 14 96.08 Very High Very High Very High
Autoimmune Disease 10 92.88 High High
Disease Susceptibility 1 85.60 High High
Disease 37 82.40 Quite High
Liver Disease 9 70.52 Quite High
Primary Sclerosing Cholangitis 7 64.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For instance, CYP1A2 is the molecular target in dihydralazine-induced hepatitis and AIH as a component of APECED, CYP2D6 in AIH-2 and in some patients with HCV infection, CYP2A6 in APECED and in a proportion of patients with HCV infection and UGT1 in some cases of AIH-2 and chronic hepatitis D or C.
CYP2A6 Regulation (target) of CYP2D6 associated with chronic hepatitis, autoimmune hepatitis, hepatitis c virus infection, infection and hepatitis
1) Confidence 0.05 Published 2004 Journal J Autoimmune Dis Section Body Doc Link PMC544946 Disease Relevance 2.01 Pain Relevance 0.05

General Comments

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