INT180456

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Context Info
Confidence 0.06
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.83
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cdh23) plasma membrane (Cdh23) cilium (Cdh23)
Anatomy Link Frequency
hippocampus 1
Cdh23 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 9 98.68 Very High Very High Very High
Spinal cord 12 95.08 Very High Very High Very High
Inflammation 11 75.40 Quite High
Central nervous system 3 57.88 Quite High
Inflammatory response 8 5.00 Very Low Very Low Very Low
gABA 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 30 98.80 Very High Very High Very High
Disorder Of Lipid Metabolism 28 90.68 High High
Diabetes Mellitus 92 85.28 High High
Coronary Artery Disease 62 83.64 Quite High
Motor Neuron Diseases 107 77.84 Quite High
INFLAMMATION 20 75.40 Quite High
Stress 22 72.20 Quite High
Death 19 37.92 Quite Low
Neurodegenerative Disease 9 34.08 Quite Low
Obesity 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The apo A-V is a highly responsive PPAR target gene [13].
Regulation (responsive) of A-V
1) Confidence 0.06 Published 2005 Journal Lipids Health Dis Section Body Doc Link PMC545942 Disease Relevance 0.93 Pain Relevance 0
The apo A-V is a highly responsive PPAR target gene [13].
Regulation (target) of A-V
2) Confidence 0.06 Published 2005 Journal Lipids Health Dis Section Body Doc Link PMC545942 Disease Relevance 0.93 Pain Relevance 0
In particular, ATP1A3, EGR1, and CHGB experience opposing deregulation in the SALS motor cortex compared to the AD hippocampus, with ANXA2, ATP6V1A, EIF4A2, NSF, and all the metallothioneins detected in the hippocampus (MT1E, MT1G, MT1X, MT2A) also showing markedly different regulation between both tissues.


Regulation (deregulation) of SALS in hippocampus associated with hippocampus and disease
3) Confidence 0.03 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1796866 Disease Relevance 0.97 Pain Relevance 0.32

General Comments

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