INT180487

Context Info Confidence 0.39 First Reported 2005 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 3.91 Pain Relevance 0

SLITRK1 (Homo sapiens)

Pain Link Frequency Relevance Heat sSRI 12 5.00 antagonist 9 5.00 Opioid 9 5.00 fluoxetine 7 5.00 behavioral therapy 6 5.00 depression 5 5.00 antidepressant 3 5.00 addiction 3 5.00 carbamazepine 2 5.00 agonist 2 5.00

Disease Link Frequency Relevance Heat Impulse Control Disorders 239 100.00 Anxiety Disorder 167 98.84 Compulsive Personality Disorder 3 70.56 Personality Disorder 2 70.32 Hypochondriasis 2 69.24 Panic Disorder 5 68.00 Affective Disorder 4 66.96 Depression 10 66.52 Injury 9 59.28 Obsessive-compulsive Disorder 9 50.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In addition, patients with TTM recognize the behavior as senseless, undesirable and performed in response to increasing anxiety, with resultant tension relief.

TTM Binding (recognize) of associated with anxiety disorder and impulse control disorders

1) Confidence 0.39 Published 2006 Journal Eur Arch Psychiatry Clin Neurosci Section Body Doc Link PMC1705499 Disease Relevance 1.80 Pain Relevance 0

However, the impairment and distress due to TTM should not be underestimated: TTM can be associated with serious sociological and psychological effects (e.g. strong feelings of shame and embarrassment [42], as well as avoidance behaviour including potentially dangerous avoidance of medical care [43]) resulting in a significant decline in quality of life (QOL) for patients, their family members and significant others [44,45].

TTM Binding (associated) of associated with impulse control disorders

2) Confidence 0.16 Published 2005 Journal BMC Psychiatry Section Body Doc Link PMC546013 Disease Relevance 2.11 Pain Relevance 0

General Comments

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