INT180532

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Context Info
Confidence 0.58
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.15
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (BPI) extracellular region (BPI) cytoplasm (BPI)
Anatomy Link Frequency
neutrophils 1
BPI (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 1 86.52 High High
Inflammation 8 85.80 High High
Pain 1 33.12 Quite Low
rheumatoid arthritis 1 32.08 Quite Low
cytokine 16 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 2 98.68 Very High Very High Very High
Lymphopenia 2 90.60 High High
Pulmonary Fibrosis 1 86.52 High High
Malignant Neoplastic Disease 1 86.16 High High
INFLAMMATION 11 85.80 High High
Cancer 6 79.40 Quite High
Adult Respiratory Distress Syndrome 2 76.32 Quite High
Respiratory Distress 1 73.80 Quite High
Severe Acute Respiratory Syndrome 48 73.52 Quite High
Apoptosis 3 69.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Currently, BPI is not really supported by most public-domain pathway editors.
Neg (not) Localization (supported) of BPI
1) Confidence 0.58 Published 2010 Journal Nucleic Acids Research Section Body Doc Link PMC2896112 Disease Relevance 0.24 Pain Relevance 0
BPI is released from activated neutrophils and is an endogenous antibiotic, which rapidly kills Gram negative bacteria by high affinity binding to the LPS component of the cell wall [25].
Localization (released) of BPI in neutrophils
2) Confidence 0.19 Published 2005 Journal BMC Immunol Section Body Doc Link PMC546205 Disease Relevance 0.91 Pain Relevance 0.12

General Comments

This test has worked.

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