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Context Info
Confidence 0.34
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.37
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (COL1A1) extracellular region (COL1A1) cytoplasm (COL1A1)
COL1A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 2 56.56 Quite High
rheumatoid arthritis 35 50.00 Quite Low
methotrexate 2 47.40 Quite Low
carpal tunnel syndrome 6 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lysosome Storage Disease 7 100.00 Very High Very High Very High
Mucopolysaccharidosis I 28 99.66 Very High Very High Very High
Adhesions 1 73.04 Quite High
Rheumatoid Arthritis 35 50.00 Quite Low
Disease 31 26.56 Quite Low
Disease Progression 3 21.52 Low Low
Syndrome 8 19.36 Low Low
Contracture 14 5.00 Very Low Very Low Very Low
Hernia 13 5.00 Very Low Very Low Very Low
Osteoporosis 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunofluorescence microscopy of collagen I
Phosphorylation (microscopy) of collagen I
1) Confidence 0.34 Published 2010 Journal Biomed Eng Online Section Body Doc Link PMC2837661 Disease Relevance 0.07 Pain Relevance 0
HRT caused a pronounced decrease in the collagen type I degradation marker, CTX-I, both when the HRT and control groups were compared (P < 0.001) and within the HRT group (P < 0.001) (Fig. 1a).
Phosphorylation (marker) of collagen type I
2) Confidence 0.13 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC546286 Disease Relevance 0 Pain Relevance 0.03
Timely recognition and accurate diagnosis of Scheie syndrome, the attenuated form of mucopolysaccharidosis type I (MPS I; OMIM#252800), have acquired greater urgency with the advent of enzyme replacement therapy (ERT) as an etiologic treatment option for this rare lysosomal storage disorder (Clarke et al. 2009; Giugliani et al. 2009; Kakkis et al. 2001; Wraith et al. 2004).
Phosphorylation (form) of mucopolysaccharidosis type I associated with mucopolysaccharidosis i and lysosome storage disease
3) Confidence 0.02 Published 2010 Journal J Inherit Metab Dis Section Body Doc Link PMC2903709 Disease Relevance 0.29 Pain Relevance 0

General Comments

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