INT180681

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Context Info
Confidence 0.44
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.48
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
stroma 1
central vein 1
Mmp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 48 100.00 Very High Very High Very High
cytokine 8 98.76 Very High Very High Very High
chemokine 4 92.08 High High
fibrosis 30 73.76 Quite High
Inflammation 4 59.72 Quite High
Pain 1 39.44 Quite Low
tolerance 7 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Dismenorea 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 32 99.48 Very High Very High Very High
Metastasis 10 99.04 Very High Very High Very High
Hepatotoxicity 8 84.96 Quite High
Cancer 54 84.64 Quite High
Toxicity 10 81.12 Quite High
Liver Disease 10 76.64 Quite High
Pathologic Processes 1 74.12 Quite High
Syndrome 1 74.00 Quite High
Disease 4 73.36 Quite High
Hepatomegaly 3 72.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The indirect action of these molecules through MMPs may aid to generate different changes in the endometrial stroma during maternal recognition of pregnancy [44]
Regulation (molecules) of MMP in stroma
1) Confidence 0.44 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC548144 Disease Relevance 0 Pain Relevance 0.19
Cells positive for MMPs and TIMPs in the portal areas and around the central vein also showed ?
Regulation (positive) of MMP in central vein associated with metalloproteinase
2) Confidence 0.44 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2844613 Disease Relevance 1.06 Pain Relevance 0.47
Several reports have suggested molecular mechanisms that radiation might enhance metastasis.85,86 Cheng, et al.85 showed that radiation up-regulates prometastatic molecule, matrix metalloproteinase (MMP)-9.
Regulation (regulates) of MMP associated with metalloproteinase and metastasis
3) Confidence 0.26 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2768232 Disease Relevance 1.42 Pain Relevance 0.05

General Comments

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