INT180772

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Context Info
Confidence 0.11
First Reported 2005
Last Reported 2005
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.29
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) extracellular region (Bdnf) plasma membrane (Trpv1)
cytoplasmic membrane-bounded vesicle (Bdnf) lipid metabolic process (Trpv1)
Bdnf (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 200 99.80 Very High Very High Very High
qutenza 104 96.28 Very High Very High Very High
Calcitonin gene-related peptide 192 95.84 Very High Very High Very High
trigeminal ganglion 118 86.48 High High
Neuropeptide 22 50.00 Quite Low
Trigeminal ganglion neurons 2 50.00 Quite Low
Migraine 12 46.68 Quite Low
antagonist 2 27.52 Quite Low
dorsal root ganglion 24 25.52 Quite Low
Inflammation 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 146 86.48 High High
Headache 12 46.68 Quite Low
Disease 4 43.36 Quite Low
Nociception 16 15.52 Low Low
Injury 46 5.00 Very Low Very Low Very Low
Hyperalgesia 14 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Nervous System Injury 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NGF, GDNF or BDNF (100 ng/ml) did not significantly alter TRPV1 mRNA levels after 5 days of treatment (Fig. 4).
BDNF Neg (not) Regulation (alter) of TRPV1 mRNA associated with nerve growth factor
1) Confidence 0.11 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.15 Pain Relevance 0.25
BDNF effects on TRPV1 protein levels were not assessed, because preliminary studies indicated that BDNF did not influence CAP-evoked CGRP release.


BDNF Regulation (effects) of TRPV1 protein associated with qutenza and calcitonin gene-related peptide
2) Confidence 0.11 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.14 Pain Relevance 0.64

General Comments

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