INT180779

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Context Info
Confidence 0.09
First Reported 2005
Last Reported 2005
Negated 3
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.23
Pain Relevance 2.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf, Calca) extracellular space (Calca) aging (Calca)
nucleus (Calca) intracellular (Calca) cytoplasmic membrane-bounded vesicle (Bdnf)
Bdnf (Rattus norvegicus)
Calca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 288 100.00 Very High Very High Very High
qutenza 156 100.00 Very High Very High Very High
Nerve growth factor 300 98.88 Very High Very High Very High
nociceptor 18 86.80 High High
trigeminal ganglion 177 84.64 Quite High
Neuropeptide 33 50.00 Quite Low
Trigeminal ganglion neurons 3 50.00 Quite Low
Migraine 18 19.36 Low Low
dorsal root ganglion 36 5.00 Very Low Very Low Very Low
Inflammation 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 219 84.64 Quite High
Headache 18 19.36 Low Low
Disease 6 16.04 Low Low
Injury 69 5.00 Very Low Very Low Very Low
Nociception 24 5.00 Very Low Very Low Very Low
Hyperalgesia 21 5.00 Very Low Very Low Very Low
INFLAMMATION 15 5.00 Very Low Very Low Very Low
Pain 9 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Nervous System Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, BDNF did not alter K -evoked CGRP release.
BDNF Neg (not) Regulation (alter) of CGRP release associated with calcitonin gene-related peptide
1) Confidence 0.09 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.08 Pain Relevance 0.75
BDNF treatment did not alter the normalized CGRP content.


BDNF Neg (not) Regulation (alter) of CGRP associated with calcitonin gene-related peptide
2) Confidence 0.09 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0 Pain Relevance 1.26
BDNF effects on TRPV1 protein levels were not assessed, because preliminary studies indicated that BDNF did not influence CAP-evoked CGRP release.


BDNF Neg (not) Regulation (influence) of CGRP release associated with qutenza and calcitonin gene-related peptide
3) Confidence 0.09 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.14 Pain Relevance 0.70

General Comments

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