INT180798

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.41
Pain Relevance 3.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Zbtb38) nucleus (Zbtb38) intracellular (Zbtb38)
DNA binding (Zbtb38)
Anatomy Link Frequency
neurons 3
dopaminergic neurons 1
Zbtb38 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 250 100.00 Very High Very High Very High
Calcitonin gene-related peptide 192 100.00 Very High Very High Very High
inferior alveolar nerve 302 99.84 Very High Very High Very High
tetrodotoxin 116 99.70 Very High Very High Very High
hyperexcitability 16 96.44 Very High Very High Very High
dorsal root ganglion 30 95.96 Very High Very High Very High
Nerve growth factor 208 93.12 High High
Action potential 44 84.56 Quite High
Pain 24 74.64 Quite High
allodynia 10 63.00 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 284 100.00 Very High Very High Very High
Disease 4 98.68 Very High Very High Very High
Apoptosis 4 96.76 Very High Very High Very High
Congenital Anomalies 4 75.88 Quite High
Pain 26 74.64 Quite High
Injury 58 71.76 Quite High
Neuropathic Pain 16 63.00 Quite High
Nervous System Injury 38 60.80 Quite High
Nociception 18 46.80 Quite Low
Headache 14 46.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A small number of FG-labeled neurons were observed in the TG at 7 days after IAN transection and many were evident in the TG at 14 days after IAN transection (Figure 1B and 1C).
Negative_regulation (number) of neurons in neurons associated with inferior alveolar nerve and trigeminal ganglion
1) Confidence 0.01 Published 2010 Journal Mol Pain Section Body Doc Link PMC2829527 Disease Relevance 1.12 Pain Relevance 1.07
These data suggest that the increase in both TTX-S INa and TTX-R INa and the decrease in IA and Ik in small/medium TG neurons in IAN-transected rats are involved in the activation of spike generation, resulting in hyperexcitability of A?
Negative_regulation (decrease) of neurons in neurons associated with tetrodotoxin, inferior alveolar nerve, trigeminal ganglion and hyperexcitability
2) Confidence 0.01 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2829527 Disease Relevance 0.44 Pain Relevance 1.30
BDNF treatment continued not to have an effect following normalization to the number of CGRP-immunoreactive neurons.
Negative_regulation (number) of neurons in neurons associated with calcitonin gene-related peptide
3) Confidence 0.00 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0 Pain Relevance 0.82
GDNF is protective against the loss of dopaminergic neurons in animal models of Parkinson's disease [52,53], and GDNF reduces the number of apoptotic bodies in DRG explants from adult mice [54].
Negative_regulation (loss) of neurons in dopaminergic neurons associated with dorsal root ganglion, apoptosis and disease
4) Confidence 0.00 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.85 Pain Relevance 0.40

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox