INT180801

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Context Info
Confidence 0.20
First Reported 2005
Last Reported 2005
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.31
Pain Relevance 2.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Gdnf) extracellular space (Gdnf) extracellular region (Gdnf)
Anatomy Link Frequency
outflow 2
Gdnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 200 100.00 Very High Very High Very High
intrathecal 2 99.98 Very High Very High Very High
c fibre 2 99.84 Very High Very High Very High
substance P 10 98.80 Very High Very High Very High
Neuropeptide 22 98.16 Very High Very High Very High
Thermal hyperalgesia 6 97.88 Very High Very High Very High
qutenza 104 95.44 Very High Very High Very High
trigeminal ganglion 118 94.68 High High
dorsal root ganglion 24 94.32 High High
nociceptor 12 78.96 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 14 97.88 Very High Very High Very High
Ganglion Cysts 146 94.68 High High
Nociception 16 91.16 High High
Hypersensitivity 4 83.76 Quite High
Injury 46 68.48 Quite High
INFLAMMATION 10 60.36 Quite High
Headache 12 54.88 Quite High
Nervous System Injury 4 54.80 Quite High
Disease 4 51.56 Quite High
Pain 6 21.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of NGF, GDNF or BDNF treatment on TRPV1 mRNA and protein levels
Regulation (Effects) of GDNF Binding (treatment) of associated with nerve growth factor
1) Confidence 0.20 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.33 Pain Relevance 0.39
On the other hand, intrathecal injection of GDNF has no effect on C-fiber evoked outflow of SP and does not induce thermal hyperalgesia, while NGF does both [15].
Neg (no) Regulation (effect) of GDNF Binding (injection) of in outflow associated with c fibre, nerve growth factor, thermal hyperalgesia, substance p and intrathecal
2) Confidence 0.20 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.98 Pain Relevance 1.63

General Comments

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