INT180802

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Sorbs1) cytoplasm (Sorbs1) cell proliferation (Gdnf)
cytosol (Sorbs1) extracellular space (Gdnf) extracellular region (Gdnf)
Anatomy Link Frequency
neurons 1
Gdnf (Rattus norvegicus)
Sorbs1 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 52 100.00 Very High Very High Very High
Nerve growth factor 100 99.90 Very High Very High Very High
trigeminal ganglion 59 93.64 High High
Hyperalgesia 3 92.60 High High
Pain 3 85.04 High High
Neuropeptide 11 72.32 Quite High
Calcitonin gene-related peptide 96 67.52 Quite High
Trigeminal ganglion neurons 1 50.00 Quite Low
Migraine 6 26.56 Quite Low
headache 1 20.00 Low Low
Disease Link Frequency Relevance Heat
Injury 23 99.90 Very High Very High Very High
Ganglion Cysts 73 93.64 High High
Hyperalgesia 7 92.60 High High
Pain 3 85.04 High High
Headache 6 26.56 Quite Low
Headache Disorders 1 20.64 Low Low
INFLAMMATION 5 16.12 Low Low
Nociception 8 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Nervous System Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While it has been shown, using a variety of dependent measures, that both NGF and GDNF increase CAP responsiveness [16,17], this is the first demonstration that these growth factors qualitatively alter the pharmacodynamics of the neuronal response to CAP in TG neurons.
GDNF Positive_regulation (increase) of CAP in neurons associated with qutenza, nerve growth factor and trigeminal ganglion
1) Confidence 0.02 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.98 Pain Relevance 1.34

General Comments

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