INT180862

Context Info Confidence 0.17 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.82 Pain Relevance 0

cytoskeletal protein binding (ANXA2) signal transduction (S100A10) extracellular region (ANXA2) plasma membrane (ANXA2) protein complex (ANXA2) cytoplasm (ANXA2)

ANXA2 (Homo sapiens) S100A10 (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 8 5.00 metalloproteinase 4 5.00 fibrosis 3 5.00 pain pelvic 2 5.00 Inflammatory response 1 5.00

Disease Link Frequency Relevance Heat Adhesions 127 96.44 Cancer 2 88.76 Malignant Neoplastic Disease 2 87.76 Hypoxia 21 5.00 Apoptosis 16 5.00 Injury 15 5.00 Wound Healing 5 5.00 Fibrosis 3 5.00 Death 3 5.00 Cicatrix 3 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

S100A10 proteins interact with Annexin A2 forming a heterotetrameric structure AIIt; that dock into the cell membrane promoting F-actin reorganization and cell migration [21].

Annexin A2 Binding (interact) of S100A10

1) Confidence 0.17 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC548295 Disease Relevance 0.82 Pain Relevance 0

General Comments

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