INT180976

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Context Info
Confidence 0.37
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.78
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (PASK) Golgi apparatus (PASK) nucleus (PASK)
cytoplasm (PASK) signal transducer activity (PASK)
PASK (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 46 98.64 Very High Very High Very High
depression 51 18.24 Low Low
palliative 11 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
antidepressant 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Suicidal Behaviour 339 100.00 Very High Very High Very High
Death 64 94.12 High High
Breast Cancer 59 91.28 High High
Cancer 32 42.04 Quite Low
Depression 53 18.24 Low Low
Overdose 15 5.00 Very Low Very Low Very Low
Mental Disorders 13 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 8 5.00 Very Low Very Low Very Low
Hypercalcemia 7 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The British Geriatrics Society opposes PAS and considers elderly patients to be vulnerable to its misuse [13].
Negative_regulation (opposes) of PAS associated with suicidal behaviour
1) Confidence 0.37 Published 2006 Journal BMC Fam Pract Section Body Doc Link PMC1550404 Disease Relevance 1.22 Pain Relevance 0
Inhibitors of both the PAS (aprotinin and PA inhibitor-1) and MMPs (CT1166 and tisue inhibitor of metalloproteinase) blocked collagen degradation, demonstrating the requirement of both plasminogen activation and MMP activity for degradation.
Negative_regulation (Inhibitors) of PAS associated with metalloproteinase
2) Confidence 0.05 Published 2005 Journal Cancer Cell Int Section Abstract Doc Link PMC548674 Disease Relevance 0.56 Pain Relevance 0.27

General Comments

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